Torrey E F, Rawlings R R
National Institute of Mental Health, Neuroscience Center at St Elizabeths, Washington, DC 20032, USA.
Br J Psychiatry. 1996 Dec;169(6):772-5. doi: 10.1192/bjp.169.6.772.
It has previously been reported that births of individuals who later develop schizophrenia vary by birth year.
Birth data were analysed on 34,024 individuals diagnosed with DSM-III-R disorganised, catatonic, and undifferentiated schizophrenia using time series analysis.
Minor yearly fluctuations were observed but did not achieve statistical significance. Thus earlier findings reported in the literature could not be replicated using a different statistical approach.
The findings do not support theories which assume major yearly fluctuations in the births of individuals with schizophrenia. Such theories include the perinatal effects of influenza, temperature variation, and the effects of severe weather.
此前有报道称,后来患精神分裂症的个体的出生情况随出生年份而变化。
使用时间序列分析对34024名被诊断为DSM-III-R紊乱型、紧张型和未分化型精神分裂症的个体的出生数据进行分析。
观察到每年有微小波动,但未达到统计学显著性。因此,使用不同的统计方法无法复现文献中早期报道的结果。
这些发现不支持那些假设精神分裂症患者出生情况存在重大年度波动的理论。此类理论包括流感的围产期影响、温度变化以及恶劣天气的影响。