在儿童门诊静脉穿刺术前使用复方利多卡因乳膏作为局部麻醉剂。

EMLA cream as a topical anesthetic before office phlebotomy in children.

作者信息

Young S S, Schwartz R, Sheridan M J

机构信息

Utah Valley Family Practice Residency, Provo, USA.

出版信息

South Med J. 1996 Dec;89(12):1184-7. doi: 10.1097/00007611-199612000-00010.

DOI:10.1097/00007611-199612000-00010

PMID:8969353

Abstract

We studied the effectiveness of EMLA cream (2.5% lidocaine, 2.5% prilocaine) in reducing distress, anxiety, and pain associated with phlebotomy in pediatric outpatients. This was a randomized, double-blind, placebo-controlled study using EMLA cream or placebo 1 hour before phlebotomy. Distress, anticipatory anxiety, pain, and adverse reactions were measured. Measurements of distress and ease of procedure, as well as changes in heart rate, showed significant improvement with EMLA cream as compared with placebo. Pain was decreased with use of EMLA cream. Anticipatory anxiety levels were equal within both groups. Ratings of cream efficacy by parent/observer scales were in favor of EMLA cream.

摘要

我们研究了复方利多卡因乳膏（2.5%利多卡因，2.5%丙胺卡因）在减轻儿科门诊患者静脉穿刺所致的痛苦、焦虑和疼痛方面的有效性。这是一项随机、双盲、安慰剂对照研究，在静脉穿刺前1小时使用复方利多卡因乳膏或安慰剂。对痛苦、预期性焦虑、疼痛和不良反应进行了测量。与安慰剂相比，复方利多卡因乳膏在痛苦程度和操作难易程度的测量以及心率变化方面均显示出显著改善。使用复方利多卡因乳膏可减轻疼痛。两组的预期性焦虑水平相当。家长/观察者量表对乳膏疗效的评分支持复方利多卡因乳膏。