Kalogeromitros D, Armenaka M, Galatas I, Capellou O, Katsarou A
Department of Dermatology, University of Athens A Sygros Hospital, Greece.
Ann Allergy Asthma Immunol. 1996 Dec;77(6):480-2. doi: 10.1016/S1081-1206(10)63354-6.
The legume food family is large and includes peanut and soybean, two of the most frequent causes of food allergy. Literature on type I hypersensitivity to lentils, also a legume, is scarce.
To describe a child with repeated anaphylactic reactions related to lentils.
Skin prick tests with both commercial and cooked extracts and serum-specific IgE measured by CAP-RIA were used to identify specific IgE antibodies to various legumes.
An 8-year-old girl suffered four episodes of anaphylaxis related to lentils from ages 3 to 7 years. The first three involved ingestion of cooked lentils and each time smaller amounts induced symptoms. The fourth episode occurred with inhalation exposure to cooking lentil soup. Subsequently, she presented with contact urticaria from raw chickpeas and an anaphylactic reaction after ingestion of cooked chickpeas. Prick tests showed strongly positive reactions to lentil and chickpea and weaker positive reactions to peanut, pea, soybean, and white bean. CAP-RIA was class 6 to lentil; class 5 to peanut, pea, and soybean; class 4 to white bean, and class 0 to green bean.
Severe type I hypersensitivity to lentils occurred in this patient and was associated with clinically relevant hypersensitivity to chickpeas. Prick tests and CAP-RIA demonstrated multiple positive reactions to other legumes.
豆科食物种类繁多，包括花生和大豆，这两种是食物过敏最常见的诱因。关于对同为豆科植物的小扁豆发生I型超敏反应的文献较少。
描述一名与小扁豆相关的反复发生过敏反应的儿童。
采用市售提取物和煮熟提取物进行皮肤点刺试验，并通过化学发光免疫分析法（CAP-RIA）检测血清特异性IgE，以鉴定针对各种豆类的特异性IgE抗体。
一名8岁女孩在3至7岁期间发生了4次与小扁豆相关的过敏反应。前三次是摄入煮熟的小扁豆，每次食用量越少症状越轻。第四次发作是在吸入煮小扁豆汤的气味时发生的。随后，她出现了生鹰嘴豆引起的接触性荨麻疹以及食用煮熟鹰嘴豆后的过敏反应。点刺试验显示对小扁豆和鹰嘴豆呈强阳性反应，对花生、豌豆、大豆和白豆呈弱阳性反应。化学发光免疫分析法检测结果显示，对小扁豆为6级；对花生、豌豆和大豆为5级；对白豆为4级；对绿豆为0级。
该患者对小扁豆发生严重的I型超敏反应，并与对鹰嘴豆的临床相关超敏反应有关。点刺试验和化学发光免疫分析法显示对其他豆类有多种阳性反应。
