Miyazono N, Ueno K, Nakajo M, Nishida H, Inoue H, Tsuchimochi S, Hokotate H, Yoshida H
Department of Radiology, Faculty of Medicine, Kagoshima University, Japan.
Invest Radiol. 1996 Dec;31(12):755-60. doi: 10.1097/00004424-199612000-00004.
The authors compared the embolic effect of radiolucent absolute ethanol (AE) with that of a radiopaque iohexol-ethanol (IES) solution for renal ablation in dogs and for the destruction of human aldosteronomas by the technique of transcatheter arterial embolization (TAE) to test whether IES can be an alternative to AE.
The embolic agents were infused through a balloon catheter into the renal arteries of 17 dogs (9 infused with 0.3 mL/kg AE; 8 infused with IES). The immediate and parenchyma were compared between the two groups. Transcatheter arterial embolization with IES also was performed in three humans with unilateral aldosteronoma.
The IES was visualized faintly under fluoroscopy in all dogs. There were no significant differences in embolic effects between the AE and IES. Three patients with aldosteronoma were treated successfully by TAE with IES.
The IES can be used as a "visible ethanol" to improve the safety and ease of ethanol embolization.
作者比较了透光性无水乙醇（AE）与不透射线的碘海醇 - 乙醇（IES）溶液在犬肾消融及经导管动脉栓塞术（TAE）破坏人醛固酮瘤方面的栓塞效果，以测试IES是否可替代AE。
通过球囊导管将栓塞剂注入17只犬的肾动脉（9只注入0.3 mL/kg AE；8只注入IES）。比较两组的即刻及实质情况。对3例单侧醛固酮瘤患者也进行了IES经导管动脉栓塞术。
在所有犬中，IES在荧光透视下隐约可见。AE与IES的栓塞效果无显著差异。3例醛固酮瘤患者通过IES TAE治疗成功。
IES可用作“可视乙醇”，以提高乙醇栓塞的安全性和便利性。
