Elzouki A Y, Akthar M, Mirza K
Division of Pediatric Nephrology, King Fahad Hospital, Riyadh, Saudi Arabia.
Pediatr Nephrol. 1996 Dec;10(6):748-51. doi: 10.1007/s004670050208.
We report a patient with a peculiar association of brucella endocarditis, glomerulonephritis, and renal vasculitis, with immunopathological features different from those of endocarditis glomerulonephritis. Renal biopsy revealed moderate diffuse hypercellularity involving the mesangium as well as capillary loops, immunoflurescence revealed no staining for IgG, IgM, IgA, C3, and fibrinogen. The clinical and biochemical evidence of glomerulonephritis disappeared after antibiotic treatment combined with steroid therapy. No similar case has been previously reported in the literature.
我们报告了一名患有布鲁氏菌性心内膜炎、肾小球肾炎和肾血管炎特殊关联的患者，其免疫病理特征与心内膜炎肾小球肾炎不同。肾活检显示系膜和毛细血管袢中度弥漫性细胞增多，免疫荧光显示IgG、IgM、IgA、C3和纤维蛋白原无染色。抗生素治疗联合类固醇治疗后，肾小球肾炎的临床和生化证据消失。此前文献中未见类似病例报道。
