医学与医学和手术治疗布氏杆菌性心内膜炎。
Medical versus medical and surgical treatment for brucella endocarditis.
机构信息
Union Memorial Hospital, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
出版信息
Ann Thorac Surg. 2012 Dec;94(6):2141-6. doi: 10.1016/j.athoracsur.2012.07.006. Epub 2012 Oct 26.
Abstract
This review was undertaken to determine the role of surgery in the treatment of brucella endocarditis. All English and French articles reporting brucella endocarditis (1966 to 2011) in PubMed, Google, and Scopus were reviewed. In all, 308 cases were identified, and linear and logistic regression was performed. Surgery improved outcomes by decreasing mortality from 32.7% in the medical treatment only group to 6.7% in the combined surgical and medical treatment group (p<0.001). This association was still significant while controlling for other contributing factors. In the absence of a controlled trial, we recommend the utmost vigilance and consideration of surgical management in treating such patients.
摘要
这篇综述旨在确定手术在治疗布鲁氏菌性心内膜炎中的作用。检索了 PubMed、Google 和 Scopus 中所有报道布鲁氏菌性心内膜炎（1966 年至 2011 年）的英文和法文文章。共确定了 308 例病例，并进行了线性和逻辑回归分析。与仅接受药物治疗组（32.7%）相比，联合手术和药物治疗组死亡率降低至 6.7%（p<0.001），手术改善了预后。即使在控制其他相关因素后，这种相关性仍然显著。在没有对照试验的情况下，我们建议在治疗此类患者时保持高度警惕并考虑手术治疗。
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