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铜矿区居民肾皮质和肝脏中镉、锌和铜的含量。

The levels of cadmium, zinc and copper in the renal cortex and liver of the inhabitants of the copper basin.

作者信息

Orłowski C, Piotrowski J K, Kubów M

机构信息

Department of Toxicological Chemistry Medical University, Lodz, Poland.

出版信息

Int J Occup Med Environ Health. 1996;9(3):255-63.

PMID:8972168
Abstract

Tissues were analysed from 60 subjects deceased at the age of 18-82 (mean 49 years), inhabitants of the southwestern region of Poland (Legnica Copper Basin). Mean cadmium, zinc and copper concentrations determined by flame AAS were for renal cortex 41.8; 47.8 and 2.3 micrograms Me/g tissue, respectively. The respective levels in the liver were 2.3; 51.6 and 4.6 micrograms Me/g tissue (w.w.). A broad range of cadmium levels was found in renal cortex (4.2-129.3.micrograms/g), with the highest values in the 40-60 age group. The effect of tobacco smoking is more evident than in other countries: 26.3 micrograms/g in non-smokers vs. 54.6 micrograms/g in smokers. Similar proportions were found by computing the whole body burden of cadmium. Compared with other regions of Poland the environmental exposure of humans to cadmium is moderate, however, it is higher than in other European countries.

摘要

对来自波兰西南部地区(莱格尼察铜矿区)的60名年龄在18至82岁(平均49岁)的死者的组织进行了分析。通过火焰原子吸收光谱法测定的肾皮质中镉、锌和铜的平均浓度分别为41.8;47.8和2.3微克金属/克组织。肝脏中的相应水平分别为2.3;51.6和4.6微克金属/克组织(湿重)。在肾皮质中发现了广泛的镉水平范围(4.2 - 129.3微克/克),其中40 - 60岁年龄组的值最高。吸烟的影响比其他国家更为明显:非吸烟者为26.3微克/克,吸烟者为54.6微克/克。通过计算镉的全身负担也发现了类似的比例。与波兰其他地区相比,人类对镉的环境暴露程度适中,然而,高于其他欧洲国家。

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