Wicky S, Cartei F, Mayor B, Frija J, Gevenois P A, Giron J, Laurent F, Perri G, Schnyder P
Department of Radiology, University Hospital, Lausanne, Switzerland.
Eur Radiol. 1996;6(6):826-30. doi: 10.1007/BF00240680.
Rhodococcus equi (R. equi) infections have been incidentally reported as a cause of pulmonary infection in severely immunocompromised hosts, including AIDS patients. Our purpose is to describe the radiological findings in nine AIDS patients with R. equi pneumonia assessed by bronchoalveolar lavage (BAL), biopsies, cultures of sputum, and hemocultures. All patients were examined by chest radiographs and contrast-medium-enhanced chest CT. Dense pulmonary consolidations with or without cavitations accounted for the most striking radiological patterns. Chest CT also revealed six mediastinal involvements, strongly mimicking a lymphoma. Two of them had multiple bilateral pulmonary nodular opacities. Pleural effusion was not identified. Although intensive therapies were administered, seven among nine patients died within few months. In an AIDS patient living in a rural area or exposed to horses and presenting these radiological patterns, the possibility of R. equi pneumonia should be considered in the differential diagnosis along with other infectious diseases or lymphomas.
马红球菌(R. equi)感染已被偶然报道为包括艾滋病患者在内的严重免疫功能低下宿主肺部感染的病因。我们的目的是描述9例经支气管肺泡灌洗(BAL)、活检、痰培养和血培养评估的艾滋病合并马红球菌肺炎患者的影像学表现。所有患者均接受了胸部X线片和对比剂增强胸部CT检查。伴有或不伴有空洞的肺部致密实变是最显著的影像学表现。胸部CT还显示6例纵隔受累,强烈提示淋巴瘤。其中2例有多发双侧肺结节状混浊。未发现胸腔积液。尽管给予了强化治疗,但9例患者中有7例在数月内死亡。对于生活在农村地区或接触过马匹且出现这些影像学表现的艾滋病患者,在鉴别诊断中应考虑马红球菌肺炎的可能性,同时也要考虑其他传染病或淋巴瘤。