Gerwick W H
College of Pharmacy, Oregon State University, Corvallis 97331, USA.
Lipids. 1996 Dec;31(12):1215-31. doi: 10.1007/BF02587906.
Marine organisms, especially marine algae, are extremely rich in a diversity of novel oxylipin structures. Many of these oxylipins contain functionalities and rings of a type and location unknown in mammalian systems. In this perspective reviewing marine oxylipins, a proposal is formulated for the central intermediacy of an epoxy allylic carbocation in the biogenesis of these diverse structures. This proposal is strengthened by the relatively large number of examples which are consistent with this type of mechanistic transformation.
海洋生物，尤其是海藻，富含多种新型氧化脂质结构。其中许多氧化脂质含有哺乳动物系统中未知类型和位置的官能团和环。在这篇关于海洋氧化脂质的综述中，提出了环氧烯丙基碳正离子在这些多样结构生物合成中起核心中间体作用的观点。与这种机理转变类型相符的例子数量相对较多，这一观点得到了强化。
