Proteau P J, Gerwick W H
College of Pharmacy, Oregon State University, Corvallis 97331.
Lipids. 1993 Sep;28(9):783-7. doi: 10.1007/BF02536231.
Three species of brown algae, Laminaria sinclairii, L. saccharina and L. setchellii, have been investigated for the presence of oxylipins. From one, L. sinclairii, three new divinyl ether fatty acids have been characterized as methyl ester derivatives (methyl 12-[1'(Z),3'(Z)-hexadienyloxy]-6(Z), 9(Z),11(E)-dodecatrienoate, methyl 12-[1'(Z),3'(Z)-hexadienyloxy]-9(Z), 11(E)-dodecadienoate, and methyl 14-[1'(Z),3'(Z)-hexadienyloxy]- 5(Z),8(Z),11(Z),13(E)-tetradecatetraenoate) by a variety of spectroscopic methods. In addition, one new [13(S)-hydroxy-6(Z),9(Z),11(E),15(Z)-octadecatetraenoic acid] and four known monohydroxy polyunsaturated fatty acids have been isolated from all three species as their methyl ester derivatives. The occurrence of these compounds in brown algae strongly suggests that these organisms possess an active lipoxygenase(s) with omega 6 specificity.
对三种褐藻，即辛克莱氏海带、糖海带和塞氏海带进行了氧化脂质的检测。从辛克莱氏海带中，通过多种光谱方法鉴定出三种新的二乙烯基醚脂肪酸甲酯衍生物（12-[1'(Z),3'(Z)-己二烯氧基]-6(Z),9(Z),11(E)-十二碳三烯酸甲酯、12-[1'(Z),3'(Z)-己二烯氧基]-9(Z),11(E)-十二碳二烯酸甲酯和14-[1'(Z),3'(Z)-己二烯氧基]-5(Z),8(Z),11(Z),13(E)-十四碳四烯酸甲酯）。此外，从这三种褐藻中均分离出一种新的[13(S)-羟基-6(Z),9(Z),11(E),15(Z)-十八碳四烯酸]和四种已知的单羟基多不饱和脂肪酸甲酯衍生物。这些化合物在褐藻中的存在有力地表明，这些生物体拥有具有ω-6特异性的活性脂氧合酶。
