Prévot S, Penna C, Imbert J C, Wendum D, de Saint-Maur P P
Department of Pathology, Saint-Antoine Hospital, Paris, France.
Mod Pathol. 1996 Dec;9(12):1170-4.
Solitary fibrous tumors are rare neoplasms, most commonly involving the pleura, recently described in various other locations. We report a solitary fibrous tumor of the right adrenal gland in a 42-year-old woman, discovered incidentally during abdominopelvic ultrasonographic examination. Pathologic and immunohistologic features of the tumor were identical to those of other solitary fibrous tumors. Three-quarters of this unencapsulated infiltrating tumoral mass presented foci of hemorrhage and were made of small, round, epithelioid-like cells that expressed the CD34 antigen more weakly than do the typical spindle cells usually observed in solitary fibrous tumors. Despite hemorrhage and poor limitation, the tumor behaved in a innocuous manner; the mass remaining unchanged for more than 5 years before the patient agreed to surgical intervention, which was recommended because of a sudden enlargement of the mass.
孤立性纤维瘤是一种罕见的肿瘤，最常累及胸膜，最近在其他各种部位也有报道。我们报告了一名42岁女性右侧肾上腺的孤立性纤维瘤，该肿瘤在腹部盆腔超声检查时偶然发现。肿瘤的病理和免疫组织学特征与其他孤立性纤维瘤相同。这个未包膜的浸润性肿瘤肿块的四分之三出现了出血灶，由小的、圆形的、上皮样细胞组成，这些细胞表达CD34抗原的程度比孤立性纤维瘤中通常观察到的典型梭形细胞要弱。尽管有出血且边界不清，但肿瘤表现为良性；在患者同意手术干预之前，肿块在5年多的时间里保持不变，手术干预是因为肿块突然增大而被推荐的。
