Geller D A, Biederman J, Griffin S, Jones J, Lefkowitz T R
Pediatric Psychopharmacology Unit, McLean Hospital, Belmont, MA 02178, USA.
J Am Acad Child Adolesc Psychiatry. 1996 Dec;35(12):1637-46. doi: 10.1097/00004583-199612000-00016.
To examine the full spectrum of psychiatric comorbidity in juvenile obsessive-compulsive disorder (OCD) in a naturalistic manner when no exclusionary criteria are used for sample selection.
Consecutive referrals to a specialized pediatric OCD clinic were evaluated by means of structured diagnostic interviews and rating scales. No exclusionary criteria were used for sample selection. Findings were compared with those of previously published reports of juvenile OCD.
Compared with previous studies, our sample of juveniles with OCD had high rates of comorbidity not only with tic, mood, and anxiety disorders but also with disruptive behavior disorders.
Our findings indicate that in the naturalistic setting, juvenile OCD is heavily comorbid with both internalizing and externalizing disorders. The presence of such a complex comorbid state has important clinical and research implications and stresses the relevance of limiting exclusionary criteria in studies of juvenile OCD.
在不使用样本选择排除标准的情况下，以自然主义的方式研究青少年强迫症（OCD）患者精神共病的全貌。
通过结构化诊断访谈和评定量表，对连续转诊至一家专门的儿科强迫症诊所的患者进行评估。样本选择不使用排除标准。将研究结果与之前发表的青少年强迫症报告结果进行比较。
与之前的研究相比，我们的青少年强迫症样本不仅与抽动障碍、情绪障碍和焦虑症共病率高，还与破坏性行为障碍共病率高。
我们的研究结果表明，在自然主义环境中，青少年强迫症与内化性和外化性障碍都有严重的共病情况。这种复杂共病状态的存在具有重要的临床和研究意义，并强调了在青少年强迫症研究中限制排除标准的相关性。
