Bíres J, Bartko P, Jencík F, Michna A, Bíresová M, Weissová T
University of Veterinary Medicine, Kosice, Slovak Republic.
Vet Med (Praha). 1996 Oct;41(10):311-8.
Clinical pattern and dynamics of some biochemical indicators were observed in six four-year lambing ewes of the Improved Wallachian breed in the course of 32-day administration of magnesite fly ash. A daily dose of the tested fly ash with the content of 305,000 mg/kg magnesium amounted to 500 mg/kg live weight of sheep. The intake of concentrate mixture with magnesium content in the test sheep decreased by a third between the 12th and 20th day, by another half between the 20th and 26th day and the intake was minimum to nil during the last seven days of the trial. The decrease in the intake of concentrate mixture was accompanied by increased water consumption and by gradual inappetence for hay. Shaped droppings started to change their consistency to slurry consistency from the 12th day of observation. Thinner to watery consistency of excrements appeared in all sheep between the 15th and 20th day and diarrheas persisted in all animals until the end of the trial. The indicators of hematological profile did not show an undoubted relationship to the administration of tested magnesium, and the variations in the particular indicators observed during the trial were within the physiological range. Serum enzymes showed a significant increase against the starting values only in the concentration of alanine aminotransferase on day 20 and day 26 (p < 0.05 and/or p < 0.001). An increase in the proteosynthetic activity of hepatocytes signalled a statistically significant increase in total proteins (p < 0.05), total immunoglobulins (p < 0.05) and an insignificant increase in albumin content. Out of the analyzed mineral elements, magnesium content showed the most significant relationship to administration of industrial pollutants as its significant increase in blood serum, urine and droppings was observable since day 20 (p < 0.05, p < 0.01 and p < 0.001, respectively). The dynamics of calcium, phosphorus, potassium, sodium, iron, copper, zinc, molybdenum, arsenic and cadmium concentrations showed different patterns in the blood serum, droppings and urine of sheep in the course of magnesite fly ash feeding, and the evaluation of interactions with magnesium requires further studies.
在对6只改良瓦拉几亚品种的四年生产羔母羊施用菱镁矿粉煤灰的32天过程中，观察了一些生化指标的临床模式和动态变化。受试粉煤灰的日剂量为每千克羊活重500毫克，其中镁含量为305,000毫克/千克。试验羊的浓缩混合料摄入量在第12天至第20天之间减少了三分之一，在第20天至第26天之间又减少了一半，在试验的最后七天摄入量降至最低或为零。浓缩混合料摄入量的减少伴随着饮水量的增加以及对干草逐渐失去食欲。从观察的第12天起，成形粪便开始变为浆状。在第15天至第20天期间，所有绵羊的粪便都变得更稀至水样，腹泻在所有动物中持续到试验结束。血液学指标与受试镁的施用没有明确的关系，试验期间观察到的特定指标变化在生理范围内。血清酶仅在第20天和第26天的丙氨酸氨基转移酶浓度相对于起始值有显著增加（p < 0.05和/或p < 0.001）。肝细胞蛋白质合成活性的增加表明总蛋白（p < 0.05）、总免疫球蛋白（p < 0.05）有统计学显著增加，白蛋白含量有不显著增加。在所分析的矿质元素中，镁含量与工业污染物的施用关系最为显著，因为从第20天起，血清、尿液和粪便中的镁含量显著增加（分别为p < 0.05、p < 0.01和p < 0.001）。在饲喂菱镁矿粉煤灰的过程中，绵羊血清、粪便和尿液中钙、磷、钾、钠、铁、铜、锌、钼、砷和镉浓度的动态变化呈现出不同模式，与镁的相互作用评估需要进一步研究。
