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[低温状态下生理功能的变化、其恢复机制及生命的温度极限]

[Changes in the physiological functions, the mechanisms of their recovery and the temperature limits for life under hypothermia].

作者信息

Ivanov K P

出版信息

Usp Fiziol Nauk. 1996 Jul-Sep;27(3):84-105.

PMID:8975507
Abstract

On the basis of the newest literature and author's own investigations the variations of the main life ensuring functions (the minute volume of respiration, the oxygen transport functions of the blood, the tissue oxygen supply ect) are analyzed under the immersion hypothermia in homoisothermal animals and man. The mechanisms of these function variations under hypothermia of various degree are described. On the basis of the newest theories of cold action on a cell the main physiological mechanisms of oppressing these functions are described, which result in the loss of homoiothermy. The possibilities and regularities of the physiological function resuscitation after deep hypothermia are analyzed. The factors, influencing the level of the lower temperature limit of life in homoiothermal animals, are determined.

摘要

根据最新文献及作者自身的研究,对恒温动物和人类在浸入性低温状态下主要生命维持功能(呼吸分钟量、血液的氧运输功能、组织氧供应等)的变化进行了分析。描述了不同程度低温下这些功能变化的机制。基于关于寒冷对细胞作用的最新理论,阐述了抑制这些功能导致体温调节丧失的主要生理机制。分析了深度低温后生理功能复苏的可能性和规律。确定了影响恒温动物生命低温下限水平的因素。

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Neurosci Behav Physiol. 2007 Jan;37(1):19-26. doi: 10.1007/s11055-007-0144-y.
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The temperature sensitivity of the cholinergic responses of cortical neurons in the guinea pig brain.
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