编码磷脂酶A2-L亚型（PLA2L）的基因定位于人类染色体8q24-qter。

Localization of a gene coding for the phospholipase A2-L subtype (PLA2L) to human chromosome 8q24-qter.

作者信息

Meyer A H, Schmuck K, Morel C, Wishart W, Lübbert H, Engels P

机构信息

Preclinical Research, Sandoz Pharma Limited, Basel, CH-4002, Switzerland.

出版信息

Genomics. 1996 Dec 15;38(3):435-7. doi: 10.1006/geno.1996.0650.

DOI:10.1006/geno.1996.0650

PMID:8975724

Abstract

Phospholipases A2 (PLA2) form an extended class of enzymes that play an important role in signal transduction. Phospholipase A2-like (PLA2L) belongs to the secreted forms of phospholipases A2, but constitutes a new subgroup. We have assigned the gene for this enzyme to human chromosome 8q24-qter using fluorescence in situ hybridization and radiation hybrid mapping techniques.

摘要

磷脂酶A2（PLA2）构成了一类广泛的酶，它们在信号转导中发挥着重要作用。类磷脂酶A2（PLA2L）属于分泌型磷脂酶A2，但构成一个新的亚组。我们使用荧光原位杂交和辐射杂种图谱技术将该酶的基因定位到人类染色体8q24 - qter上。