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英国和爱尔兰感染艾滋病毒女性的医疗干预措施采用情况。医学研究委员会女性艾滋病毒感染协作研究小组

Uptake of medical interventions in women with HIV infection in Britain and Ireland. Study Group for the MRC Collaborative Study of HIV Infection in Women.

作者信息

Mercey D, Griffioen A, Woronowski H, Stephenson J

机构信息

Academic Department of Gentiourinary Medicine, University College London Medical School, Mortimer Market Centre, UK.

出版信息

Genitourin Med. 1996 Aug;72(4):281-2. doi: 10.1136/sti.72.4.281.

Abstract

OBJECTIVE

To determine the uptake of medical interventions amongst women known to be HIV positive and in contact with service providers.

SUBJECTS

400 HIV positive women from 15 STD/HIV clinics in Britain and Ireland recruited to the MRC collaborative study of HIV infection in women between June 1992 and August 1994.

METHODS

Data obtained prospectively through direct questioning of all women by a physician or research nurse and review of medical and laboratory records. Data recorded on standardised forms and analysed centrally.

RESULTS

Nearly one quarter (24%) of women with an AIDS diagnosis had never received Pneumocystis carinii pneumonia prophylaxis, and 24% had never received any antiretroviral therapy. Fewer than two-thirds of black African women had had a chest radiograph. Only one woman had received Pneumovax and only 4% of women had ever taken part in a clinical trial.

CONCLUSIONS

A substantial proportion of women with HIV infection did not receive interventions of proven benefit, and participation in clinical trials was very uncommon. The reasons for such poor uptake should be explored among both health care workers and women with HIV infection.

摘要

目的

确定已知感染艾滋病毒且与服务提供者有接触的女性对医学干预措施的接受情况。

研究对象

1992年6月至1994年8月期间,从英国和爱尔兰的15家性传播疾病/艾滋病毒诊所招募的400名艾滋病毒阳性女性,参与医学研究委员会关于女性艾滋病毒感染的合作研究。

方法

通过医生或研究护士直接询问所有女性,并查阅医疗和实验室记录,前瞻性地获取数据。数据记录在标准化表格上并进行集中分析。

结果

近四分之一(24%)被诊断患有艾滋病的女性从未接受过卡氏肺孢子虫肺炎预防治疗,24%的女性从未接受过任何抗逆转录病毒治疗。不到三分之二的非洲黑人女性进行过胸部X光检查。只有一名女性接种过肺炎疫苗,只有4%的女性曾参与过临床试验。

结论

相当一部分感染艾滋病毒的女性没有接受已证实有益的干预措施,参与临床试验的情况也非常罕见。医护人员和感染艾滋病毒的女性都应探究接受率如此之低的原因。

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