Matani Y, Mottrie A M, Stöckle M, Voges G E, Fichtner J, Hohenfellner R
Department of Urology, Mainz Medical School, Germany.
Eur Urol. 1996;30(4):414-7. doi: 10.1159/000474208.
In a retrospective analysis, the medical records of 166 patients over 80 years of age (80-99 years, mean age 82 years) who underwent transurethral prostatectomy (TURP) for clinically benign prostatic hyperplasia (BPH) were reviewed in order to evaluate the morbidity and mortality rates in this special group of patients. The mean follow-up was 60 months (6-85 months).
According to the American Society of Anesthesiologists operative risk classification, 147 (88.5%) patients were found to be of groups ASA III and IV. All patients had at least one serious associated medical disease. Early complications occurred in 25.9% (n = 43) of patients. Late significant urology complications were noted in 13.2% (n = 22) of patients. Reoperation was carried out in 4.2% (n = 7) of cases. Two patients died within 30 days after the operation (1.2%). During the period of follow-up 43 patients died. Comparing the survival curve (according to the Kaplan-Meier analysis) of our group with the expected survival rate of the age-matched overall population, no statistical difference could be observed.
Being aware of the limits of a retrospective study, we believe that TURP as a treatment for BPH in patients over the age of 80 years has a satisfactory outcome with an acceptable morbidity and mortality rate.
在一项回顾性分析中，我们查阅了166例80岁以上（80 - 99岁，平均年龄82岁）因临床诊断为良性前列腺增生（BPH）而接受经尿道前列腺切除术（TURP）患者的病历，以评估这一特殊患者群体的发病率和死亡率。平均随访时间为60个月（6 - 85个月）。
根据美国麻醉医师协会手术风险分类，发现147例（88.5%）患者属于ASA III和IV级。所有患者至少有一种严重的相关内科疾病。25.9%（n = 43）的患者发生了早期并发症。13.2%（n = 22）的患者出现了晚期严重泌尿外科并发症。4.2%（n = 7）的病例进行了再次手术。2例患者在术后30天内死亡（1.2%）。在随访期间，43例患者死亡。将我们组的生存曲线（根据Kaplan - Meier分析）与年龄匹配的总体人群的预期生存率进行比较，未观察到统计学差异。
尽管意识到回顾性研究的局限性，但我们认为TURP作为80岁以上BPH患者的一种治疗方法，具有令人满意的结果，发病率和死亡率均可接受。
