Somyos K, Boonchu K, Somsak K, Panadda L, Leopairut J
Department of Otolaryngology, Ramathibodi Hospital, Mahidol University School of Medicine, Bangkok, Thailand.
Br J Dermatol. 1996 Dec;135(6):964-8. doi: 10.1046/j.1365-2133.1996.d01-1103.x.
Café-au-lait macules are skin lesions known to resist all kinds of treatment. Green light at a wavelength of 511 nm from a copper vapour laser through a built-in computerized scanner (SCANALL) was employed to treat café-au-lait-macules in 16 patients. The laser was used in continuous mode with a mean energy density of 8.9 J/cm2 (range 7-22 J/cm2). The mean number of treatment sessions was two. The response was good to excellent in 15 cases and poor in one. Transient hyperpigmentation at the periphery and temporary non-homogeneous hypopigmentation at the centre of the treated area was observed in some cases. These eventually returned to normal after a few months, without any textural change. Pre- and postoperative histological finding are also presented. There was no recurrence at a mean follow-up time of 22 months. Copper vapour laser is an effective modality for the treatment of café-au-lait macules.
咖啡斑是已知的对各种治疗均有抵抗性的皮肤损害。使用来自铜蒸气激光的波长为511nm的绿光，通过内置的计算机化扫描仪（SCANALL）对16例患者的咖啡斑进行治疗。激光以连续模式使用，平均能量密度为8.9J/cm²（范围为7 - 22J/cm²）。平均治疗次数为两次。15例患者的反应为良好至优秀，1例反应较差。部分病例在治疗区域周边出现短暂性色素沉着，在中心出现暂时性不均匀色素减退。这些情况在几个月后最终恢复正常，且无任何质地变化。文中还呈现了术前和术后的组织学 findings 。在平均22个月的随访时间内无复发。铜蒸气激光是治疗咖啡斑的一种有效方式。
