Artzi Ofir, Mehrabi Joseph N, Koren Amir, Niv Roni, Lapidoth Moshe, Levi Assi
Department of Dermatology, Tel Aviv Sourasky Medical Center, 6 Weizman Street, 642906, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lasers Med Sci. 2018 May;33(4):693-697. doi: 10.1007/s10103-017-2373-9. Epub 2017 Nov 2.
Café-au-lait macules (CALMs) present as benign hyperpigmented, well-circumscribed spots on the skin for which many patients seek treatment for aesthetic reasons. The objective of this study is to report our experience in treating CALMs using a picosecond 532-nm neodymium-doped yttrium aluminium garnet (PS 532 nm) laser. This is a retrospective case series of 16 patients with CALMs who were treated by a PS 532-nm laser (1-4 treatments, 4-8 weeks apart). Response as seen on clinical photographs was assessed by two independent dermatologists and graded on a scale of 0 (exacerbation) to 5 (95-100% improvement). Patient satisfaction and tolerance were documented at final visit. The results of 15 patients demonstrated significant improvement (average 3.43), and their satisfaction and tolerance levels were high. One patient had no response whatsoever to treatment. The PS 532-nm laser is a promising novel modality for the treatment of CALMs.
咖啡斑表现为皮肤上良性的色素沉着、边界清晰的斑点，许多患者因美容原因寻求治疗。本研究的目的是报告我们使用皮秒532纳米掺钕钇铝石榴石（PS 532纳米）激光治疗咖啡斑的经验。这是一项回顾性病例系列研究，对16例咖啡斑患者采用PS 532纳米激光进行治疗（1至4次治疗，每次间隔4至8周）。由两名独立的皮肤科医生根据临床照片评估疗效，并按0（恶化）至5（改善95%-100%）的等级进行评分。在末次随访时记录患者的满意度和耐受性。15例患者的治疗结果显示有显著改善（平均3.43），他们的满意度和耐受性较高。1例患者对治疗无任何反应。PS 532纳米激光是一种有前景的治疗咖啡斑的新方法。
