Triplett D A
Ball Memorial Hospital, Muncie, Indiana 47303, USA.
Haemostasis. 1996 Oct;26 Suppl 4:358-67. doi: 10.1159/000217317.
Antiphospholipid-protein antibodies (APA) are a family of immunoglobulins which recognize protein-phospholipid complexes. Among the proteins implicated are: beta 2 Glycoprotein I, prothrombin, Annexin V, protein C, and protein S. Laboratory tests are used to identify, predict potential clinical complications, and manage patients with the antiphospholipid-protein syndrome (APS). Emerging evidence suggests laboratory tests can be used to stratify relative risk of patients with APA.
抗磷脂蛋白抗体(APA)是一类识别蛋白质 - 磷脂复合物的免疫球蛋白。其中涉及的蛋白质包括:β2糖蛋白I、凝血酶原、膜联蛋白V、蛋白C和蛋白S。实验室检测用于识别、预测潜在临床并发症以及管理抗磷脂蛋白综合征(APS)患者。新出现的证据表明,实验室检测可用于对APA患者的相对风险进行分层。