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伴有高疟原虫血症的重症恶性疟:不进行换血输血的管理方法

Severe falciparum malaria with hyperparasitaemia: management without exchange blood transfusion.

作者信息

Fontes C J, Munhoz S

机构信息

Hospital Universitário Júlio Müller, School of Medicine, Federal University of Mato Grosso, Cuiabá, Brazil.

出版信息

Trop Med Int Health. 1996 Dec;1(6):820-3. doi: 10.1111/j.1365-3156.1996.tb00117.x.

DOI:10.1111/j.1365-3156.1996.tb00117.x
PMID:8980596
Abstract

The risk of complication in falciparum malaria is associated with parasite load. Drug therapy alone may be insufficient, and blood exchange transfusion is indicated when more than 10% of erythrocytes are parasitized with concurrent pulmonary, renal, cerebral or haemostatic complications; without complications, when the parasitized erythrocytes exceed 30%. The successful use of conventional malaria therapy without exchange transfusion in a young woman with severe falciparum malaria is reported.

摘要

恶性疟并发症的风险与寄生虫负荷有关。仅药物治疗可能不足,当超过10%的红细胞被寄生并伴有肺部、肾脏、脑部或止血并发症时,或无并发症但寄生红细胞超过30%时,需进行换血输血。本文报道了一名患有严重恶性疟的年轻女性未进行换血输血而成功使用传统疟疾疗法的病例。

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Exchange transfusion combined with artesunate (ET-AS) as a safe and effective therapy in severe P. falciparum malaria: a case series.青蒿琥酯联合换血疗法治疗重症恶性疟:病例系列。
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