对挪威因切尔诺贝利事故遭受放射性沉降物辐射的人员外周血淋巴细胞进行染色体分析。

Chromosome analysis of peripheral lymphocytes from persons exposed to radioactive fallout in Norway from the Chernobyl accident.

作者信息

Brøgger A, Reitan J B, Strand P, Amundsen I

机构信息

Department of Genetics, Norwegian Radium Hospital, Montebello, Oslo, Norway.

出版信息

Mutat Res. 1996 Dec 12;361(2-3):73-9. doi: 10.1016/s0165-1161(96)90241-1.

DOI:10.1016/s0165-1161(96)90241-1

PMID:8980691

Abstract

Chromosome analysis of peripheral lymphocytes from two Norwegian populations (44 reindeer herding South samis from Røros and Snåsa, 12 sheep farmers from Valdres) exposed to fallout from the Chernobyl accident were made. The doses from caesium through the years 1987-1991 were calculated based on whole-body measurements 134Cs and 137Cs giving a total cumulative mean internal dose of 5.54 mSv for the total group of 56 persons. Chromosome aberrations were within the normal range when compared with historical controls with the exception of dicentrics (0.3% per cell, which is a 10-fold increase) and rings (0.07% per cell). A dose-dependent increase in dicentrics and rings based on caesium exposure was not observed.

摘要

对来自挪威两个群体（44名来自勒罗斯和斯纳萨的驯鹿放牧萨米人、12名来自瓦尔德雷斯的牧民）的外周血淋巴细胞进行了染色体分析，这些群体曾暴露于切尔诺贝利事故的沉降物中。根据1987年至1991年期间全身测量的134铯和137铯计算出铯剂量，56人的总累积平均内照射剂量为5.54毫希沃特。与历史对照相比，染色体畸变在正常范围内，但双着丝粒（每细胞0.3%，增加了10倍）和环状染色体（每细胞0.07%）除外。未观察到基于铯暴露的双着丝粒和环状染色体的剂量依赖性增加。