Gregl A, Heitmann D, Truss F
Strahlentherapie. 1977 Aug;153(8):513-21.
During the period from 1912 through 1970, 150 cases with a carcinoma of the penis have been examined and treated in the clinics of the university of Göttingen. The preferred age of incidence was between fifty to sixty years. Primary phimosis could be verified in 17.3%, a secondary phimosis, caused by the tumor, in 5.3%. Eighty patients were graded stage I, seventy stage II and more advanced stages. Metastases to the inguinal region were observed in 60.6% out of 99 patients who had undergone lymphadenectomy. Distinctly enlarged inguinal lymph nodes proved to be metastases in only a third of the cases. The staging of a case with carcinoma of the penis, therefore, is not possible by means of clinical criteria alone but needs also a biopsy from the inguinal region. The 3-year, 5-year, and 10-year survival rates amounted to 52.5%, 46.7% and 32.4% and did not depend on treatment techniques. The most promising survival rate resulted from a combination of surgical treatment with high-voltage therapy.
在1912年至1970年期间,哥廷根大学诊所对150例阴茎癌患者进行了检查和治疗。发病的首选年龄在50至60岁之间。原发性包茎在17.3%的病例中得到证实,由肿瘤引起的继发性包茎在5.3%的病例中得到证实。80例患者为I期,70例为II期及更晚期。在接受淋巴结切除术的99例患者中,60.6%观察到腹股沟区域转移。明显肿大的腹股沟淋巴结仅在三分之一的病例中被证实为转移。因此,仅通过临床标准对阴茎癌病例进行分期是不可能的,还需要对腹股沟区域进行活检。3年、5年和10年生存率分别为52.5%、46.7%和32.4%,且不依赖于治疗技术。最有希望的生存率来自手术治疗与高压治疗的联合。