Lütolf U M, Glanzmann C, Horst W
Strahlentherapie. 1976 Oct;152(4):333-7.
The treatment and prognosis of patients suffering from penis carcinoma who were admitted at the department of radiotherapy of the Kantonsspital Zürich during the last ten years are reviewed. Based on these results which are similar to the results of other centers, we were able to show that primary radiation therapy is to be preferred regarding organ function and survival. Only is a few cases surgical intervention for recurrency was necessary. Indications for radiation therapy of lymph nodes are discussed. The five-year survival rate following primary radiation therapy amounts to 70 or 80% with early stages, a secondary surgical treatment being necessary in 5 to 20%. In more or less advanced stages, a five-year survival rate of 40 to 60% is found after primary radiation therapy, and secondary surgical treatment is needed in 20 to 50%. Thus, survival rates obtained by primary radiation therapy which was followed by an operation only in case of recurrences or tumor persistence are comparable to the recovery rates from primary surgical methods. The advantage of primary radiation therapy is evident in comparison with a surgical treatment: The organ is often saved while the survival rate is the same.
回顾了过去十年间苏黎世州立医院放疗科收治的阴茎癌患者的治疗及预后情况。基于这些与其他中心结果相似的结果，我们能够表明，就器官功能和生存率而言，首选原发性放射治疗。仅在少数复发病例中需要进行手术干预。讨论了淋巴结放射治疗的指征。早期原发性放射治疗后的五年生存率为70%或80%，其中5%至20%的患者需要进行二次手术治疗。在或多或少的晚期阶段，原发性放射治疗后五年生存率为40%至60%，20%至50%的患者需要二次手术治疗。因此，仅在复发或肿瘤持续存在时才进行手术的原发性放射治疗所获得的生存率与原发性手术方法的治愈率相当。与手术治疗相比，原发性放射治疗的优势显而易见：在生存率相同的情况下，器官常常得以保留。
