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[用于解释 32P 掺入照射或未照射实验肿瘤的体内测量结果的生化研究(作者译)]

[Biochemical investigations for interpretation of in vivo measurements of 32P-incorporation into irradiated or nonirradiated experimental tumors (author's transl)].

作者信息

Richter B, Rausch L, Breining I, Kovacs G

出版信息

Strahlentherapie. 1977 Aug;153(8):557-65.

PMID:898224
Abstract

In view of results of extracorporal measurements of the 32 P-incorporation into irradiated or nonirradiated tumors biochemical investigations of the 32P-incorporation have been performed, aiming at comprehension of the meaning and at clarification of the interpretability of these measurements. The results show that irradiation mostly decreases the content of 32P in nucleic acids. In principle, however, the latter is so low as compared to the total content of 32P, especially three hours after 32P-injection, that variations are hardly to be recorded by means of extracorporal measurements, particularly because they are superposed by changes in the 32P-content of other fractions.

摘要

鉴于对受辐照或未受辐照肿瘤进行的³²P掺入的体外测量结果,已对³²P掺入进行了生化研究,旨在理解这些测量的意义并阐明其可解释性。结果表明,辐照大多会降低核酸中³²P的含量。然而,原则上,与³²P的总含量相比,核酸中³²P的含量很低,尤其是在³²P注射三小时后,以至于通过体外测量几乎无法记录其变化,特别是因为它们被其他组分中³²P含量的变化所叠加。

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