Cherkasov O A
Tsitol Genet. 1977 Jan-Feb;11(1):66-9.
Antimutagenic activity of tryptophan in concentrations of 2-10(-3), 1-10(-2), and 5-10(-2) M was found in Allium cepa L. seedlings. These concentrations of tryptophan inhibit cell mitotic activity. By decreasing the frequency of spontaneous mutations and suppressing the mitotic activity of cells, tryptophan affects various functions of cells. The spectrum of chromosome mutations in tryptophan-treated seedlings does not differ from that observed under natural conditions.
在洋葱(Allium cepa L.)幼苗中发现了浓度为2×10⁻³、1×10⁻²和5×10⁻² M的色氨酸的抗诱变活性。这些浓度的色氨酸会抑制细胞的有丝分裂活性。通过降低自发突变的频率并抑制细胞的有丝分裂活性,色氨酸会影响细胞的各种功能。用色氨酸处理过的幼苗中的染色体突变谱与在自然条件下观察到的无异。