Simakov A A, Panfilov Iu A, Kriukov N N
Lik Sprava. 1995 Sep-Dec(9-12):34-7.
Data are submitted on the time course of immunologic indices in 50 patients with myocardial infarction (MI) presenting with complication-free course, and 58 patients with MI complicated by thromboendocarditis. Important changes were revealed in the immune status--both cellular and humoral--during the development of thrombosis of the left ventricle secondary to MI. The cellular immunity was characterized by a decline in the levels of T-lymphocytes, particularly those of T-suppressors, augmentation of B-lymphocytes. Thrombosis evolving in MI was associated with changes in humoral immunity, such as persistent and lasting rise in immunoglobulins of all classes, especially Ig G, as well as combinations thereof, together with the increase in the content of circulating immune complexes.
提交了50例无并发症心肌梗死（MI）患者和58例并发血栓性心内膜炎的MI患者免疫指标的时间进程数据。在MI继发左心室血栓形成过程中，免疫状态（包括细胞免疫和体液免疫）出现了重要变化。细胞免疫的特征是T淋巴细胞水平下降，尤其是T抑制细胞，B淋巴细胞增加。MI中发生的血栓形成与体液免疫变化有关，如所有类别的免疫球蛋白持续且持久升高，尤其是IgG及其组合，同时循环免疫复合物含量增加。
