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[急性冠状动脉循环障碍患者的细胞免疫和体液免疫]

[Cellular and humoral immunity in patients with acute disorder of coronary circulation].

作者信息

Syvolap V D, Pivovar S N, Syvolap V V

出版信息

Lik Sprava. 2003 Apr-Jun(3-4):29-31.

Abstract

The condition was studied of cell-bound and humoral immunity in patients with ischemic heart disease. The data secured permit reaching the conclusion that the unstable clinical course of angina pectoris is accompanied by unspecific alterations in the cellular link of immunity such as increase in the absolute number of T-lymphocytes and T-suppressors. In patients with myocardial infarction, in the acute period of the illness there develop inflammatory reactions involving participation of cell-bound (neutrophilic leucocytosis, a drop in the absolute number of acidophilic granulocytes, absolute number of lymphocytes, T-lymphocytes, T-suppressors, increase in T-helpers--T-suppressors ratio; decline in T-lymphocytes activity) and humoral (a drop in the level of Ig A, increase in blood serum concentration of circulating immune complexes) links of immunity.

摘要

对缺血性心脏病患者的细胞免疫和体液免疫状况进行了研究。所获得的数据使得可以得出结论:心绞痛不稳定的临床病程伴随着免疫细胞环节的非特异性改变,如T淋巴细胞和T抑制细胞绝对数量增加。在心肌梗死患者中,在疾病急性期会发生炎症反应,涉及细胞免疫(嗜中性白细胞增多、嗜酸性粒细胞、淋巴细胞、T淋巴细胞、T抑制细胞绝对数量下降、T辅助细胞与T抑制细胞比例增加;T淋巴细胞活性下降)和体液免疫(IgA水平下降、循环免疫复合物血清浓度增加)环节的参与。

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