Drucker M H, Mansour K A, Hatcher C R, Symbas P N
Ann Thorac Surg. 1979 Aug;28(2):133-8. doi: 10.1016/s0003-4975(10)63770-8.
During a 3-year period, 45 patients with esophageal carcinoma (18 of the lower and 27 of the middle third) underwent esophagectomy and esophagogastrostomy. All patients were considered to be in Stage I and Stage II preoperatively, but at the time of operation, 66% were found to have Stage III disease. All patients underwent mobilization of the stomach through a laparotomy, and resection of the esophagus and reconstruction of the continuity of the gastrointestinal tract through a separate right lateral thoracotomy incision. Following operation, 22 patients (10, Stage I and II and 12, Stage III) received no radiotherapy and 23 patients (5, Stage I and II and 18, Stage III) received radiotherapy. Two patients died in the immediate postoperative period, for a surgical mortality of 4.8%. Because of the acceptable survival and enhancement of quality of life, esophagectomy and esophagogastrostomy should be offered not only to Stage I and II patients with esophageal carcinoma but also to selected patients with Stage III disease and those with lower and middle third esophageal lesions.
在3年期间，45例食管癌患者（18例为下段，27例为中段）接受了食管切除术和食管胃吻合术。所有患者术前均被认为处于Ⅰ期和Ⅱ期，但手术时发现66%患有Ⅲ期疾病。所有患者均通过剖腹手术游离胃，并通过单独的右外侧开胸切口切除食管并重建胃肠道连续性。术后，22例患者（10例为Ⅰ期和Ⅱ期，12例为Ⅲ期）未接受放疗，23例患者（5例为Ⅰ期和Ⅱ期，18例为Ⅲ期）接受了放疗。2例患者在术后短期内死亡，手术死亡率为4.8%。由于生存率可接受且生活质量得到提高，食管切除术和食管胃吻合术不仅应提供给Ⅰ期和Ⅱ期食管癌患者，也应提供给选定的Ⅲ期疾病患者以及食管下段和中段病变患者。
