Magnuson T H, Ratner L E, Zenilman M E, Bender J S
Department of Surgery, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224, USA.
Am Surg. 1997 Jan;63(1):91-6.
Elderly patients with cholelithiasis are more likely than nonelderly patients to present with an acute complication of gallstone disease such as acute cholecystitis (AC), gallstone pancreatitis (GSP), or common bile duct stones (CBDS). These acute complications may make laparoscopic cholecystectomy (LC) more hazardous, with a potential increase in perioperative morbidity or need for open conversion. The applicability of LC in the geriatric population is, therefore, unclear. We reviewed 283 consecutive patients undergoing attempted LC. Patients were classified as presenting with complicated (AC, GSP, or CBDS) or uncomplicated gallstone disease. Elderly patients were significantly more likely than younger patients to present with AC (40% versus 18%), GSP (19% versus 6%), and CBDS (21% versus 5%) (all P < 0.05). Elderly patients with chronic, uncomplicated gallstone disease (n = 20) and nonelderly patients with uncomplicated disease (n = 159) had similar open conversion rates (5% and 7%, respectively). In contrast, the open conversion rate in elderly patients with complicated gallstone disease (n = 42) was significantly higher (50%) compared to nonelderly patients with complicated disease (n = 62; rate, 16%; P < 0.05). Perioperative morbidity and length of stay were also significantly increased in the elderly group, primarily due to the high percentage of elderly patients with complicated disease. These results suggest that elderly patients with uncomplicated gallstone disease appear to be excellent candidates for LC, and this should be considered before complicated disease develops. Conversely, early conversion or planned open cholecystectomy may be warranted in the elderly presenting with acute complications of cholelithiasis.
与非老年患者相比,老年胆石症患者更易出现胆石病的急性并发症,如急性胆囊炎(AC)、胆石性胰腺炎(GSP)或胆总管结石(CBDS)。这些急性并发症可能使腹腔镜胆囊切除术(LC)的风险更高,围手术期发病率可能增加,或需要转为开腹手术。因此,LC在老年人群中的适用性尚不清楚。我们回顾了283例连续接受LC尝试的患者。患者被分为患有复杂(AC、GSP或CBDS)或非复杂胆石病。老年患者比年轻患者更易出现AC(40%对18%)、GSP(19%对6%)和CBDS(21%对5%)(所有P<0.05)。患有慢性非复杂胆石病的老年患者(n = 20)和患有非复杂疾病的非老年患者(n = 159)的开腹手术转化率相似(分别为5%和7%)。相比之下,患有复杂胆石病的老年患者(n = 42)的开腹手术转化率(50%)明显高于患有复杂疾病的非老年患者(n = 62;转化率为16%;P<0.05)。老年组的围手术期发病率和住院时间也显著增加,主要原因是患有复杂疾病的老年患者比例较高。这些结果表明,患有非复杂胆石病的老年患者似乎是LC的理想候选人,应在复杂疾病发生前予以考虑。相反,对于出现胆石症急性并发症的老年患者,可能需要早期转为开腹手术或计划行开腹胆囊切除术。