Tuunanen T H, Ruusuvaara P J, Uusitalo R J, Tervo T M
Helsinki University Eye Hospital, Finland.
Cornea. 1997 Jan;16(1):48-53.
The efficacy and safety of excimer laser photoastigmatic refractive keratectomy (PARK) for treatment of astigmatism after penetrating keratoplasty (PKP) was evaluated in this study.
A VisX 20/20 excimer laser was used to correct the regular astigmatic component of the grafts. The epithelium was removed manually in seven cases and in three patients with the PTK mode of the laser. The results were analyzed for uncorrected visual acuity (UCVA), best corrected acuity (BCVA), haze, and changes in the cylinder and axis. The vectorial change in astigmatism was measured using Alpins' method.
Preoperative astigmatism ranged from 3.50 to 11.25 D (mean, 5.98 +/- 2.28) and the mean attempted correction of astigmatism was 6.28 +/- 1.56 D (range, 3.50-9.00 D). The induced reduction of net corneal astigmatism was 48.1%. The vector-corrected astigmatism, which was 6.40 +/- 3.49 D at 1 month postoperatively, was reduced at 12 months to 4.28 +/- 2.42 D. The Alpin Success Index varied in the range 0.06 to 1.0. Although the UCVA improved by > or = 2 lines in 60% of the eyes, the BCVA decreased in 40% of the eyes and three patients required a reoperation.
Although PARK is relatively safe and effective in reducing post-PKP cylinder and improves UCVA, the frequently and surprisingly late-developing corneal haze often impairs the BCVA.
本研究评估了准分子激光光性散光性角膜切削术(PARK)治疗穿透性角膜移植术(PKP)后散光的疗效和安全性。
使用VisX 20/20准分子激光矫正移植片的规则散光成分。7例手动去除上皮,3例采用激光的PTK模式。分析未矫正视力(UCVA)、最佳矫正视力(BCVA)、 haze以及柱镜和轴的变化。采用Alpins方法测量散光的矢量变化。
术前散光范围为3.50至11.25 D(平均,5.98±2.28),平均尝试矫正散光为6.28±1.56 D(范围,3.50 - 9.00 D)。诱导的角膜净散光减少率为48.1%。矢量矫正散光在术后1个月时为6.40±3.49 D,在12个月时降至4.28±2.42 D。Alpin成功指数在0.06至1.0范围内变化。虽然60%的眼睛UCVA提高了≥2行,但40%的眼睛BCVA下降,3例患者需要再次手术。
虽然PARK在减少PKP术后柱镜方面相对安全有效,并改善了UCVA,但频繁且令人惊讶地在后期出现的角膜 haze常常损害BCVA。