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与使用丙泊酚相关的感染风险。

Infectious risks associated with the use of propofol.

作者信息

Bach A, Motsch J

机构信息

Department of Anaesthesia, University Hospital, Heidelberg, Germany.

出版信息

Acta Anaesthesiol Scand. 1996 Nov;40(10):1189-96. doi: 10.1111/j.1399-6576.1996.tb05549.x.

DOI:10.1111/j.1399-6576.1996.tb05549.x
PMID:8986181
Abstract

BACKGROUND

Investigations of the Centers for Disease Control into postoperative infections have implicated extrinsically contaminated propofol.

METHODS

To evaluate the infectious risk associated with intravenous anaesthetic agents, we surveyed the literature from 1971 to 1995 using the Medline database. Papers covering infections related to intravenous anaesthetic agents were included.

RESULTS

The review of the literature on infections associated with propofol and other intravenous anaesthetics shows that this infectious risk is minimal and often caused by breakdowns in aseptic techniques.

CONCLUSIONS

We conclude that, if standard hygienic precautions are taken, the risk of in-use contamination of intravenous anaesthetics is low. If strict hygienic guidelines are followed in handling propofol, this agent can be safely administered to patients.

摘要

背景

疾病控制中心对术后感染的调查表明丙泊酚受到外部污染。

方法

为评估静脉麻醉剂相关的感染风险,我们使用医学在线数据库(Medline)检索了1971年至1995年的文献。纳入了涉及静脉麻醉剂相关感染的论文。

结果

对丙泊酚及其他静脉麻醉剂相关感染的文献综述表明,这种感染风险极小,且通常由无菌技术失误导致。

结论

我们得出结论,若采取标准的卫生预防措施,静脉麻醉剂在使用过程中被污染的风险较低。若在处理丙泊酚时遵循严格的卫生指南,该药物可安全地给予患者。

相似文献

1
Infectious risks associated with the use of propofol.与使用丙泊酚相关的感染风险。
Acta Anaesthesiol Scand. 1996 Nov;40(10):1189-96. doi: 10.1111/j.1399-6576.1996.tb05549.x.
2
[Infectious disease risk associated with contaminated propofol anesthesia, 1989-2014].[1989 - 2014年与丙泊酚麻醉污染相关的传染病风险]
Rev Chilena Infectol. 2016 Aug;33(4):478. doi: 10.4067/S0716-10182016000400018.
3
Postsurgical Candida albicans infections associated with an extrinsically contaminated intravenous anesthetic agent.与外在污染的静脉麻醉剂相关的术后白色念珠菌感染。
J Clin Microbiol. 1999 May;37(5):1398-403. doi: 10.1128/JCM.37.5.1398-1403.1999.
4
Efficacy of specific aseptic precautions for preventing propofol-related infections: analysis by a quality-assurance programme using the explicit outcome method.预防丙泊酚相关感染的特定无菌预防措施的效果:采用明确结果法的质量保证计划分析
J Hosp Infect. 1998 May;39(1):67-70. doi: 10.1016/s0195-6701(98)90245-6.
5
Infections linked to lax handling of propofol.与丙泊酚处理不当相关的感染。
Am J Health Syst Pharm. 1995 Oct 1;52(19):2061, 2066. doi: 10.1093/ajhp/52.19.2061.
6
Infectious Disease Risk Associated with Contaminated Propofol Anesthesia, 1989-2014(1).1989 - 2014年与污染丙泊酚麻醉相关的传染病风险(1)
Emerg Infect Dis. 2016 Jun;22(6):981-92. doi: 10.3201/eid2206.150376.
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Propofol and postoperative infections.丙泊酚与术后感染
Ann Pharmacother. 1997 Dec;31(12):1521-3.
8
[Infectious complications linked to the use of Diprivan. Precaution of administration].[与丙泊酚使用相关的感染性并发症。给药注意事项]
Ann Fr Anesth Reanim. 1994;13(4):457-9. doi: 10.1016/s0750-7658(05)80671-9.
9
In-use contamination of propofol. A clinical study.
Eur J Anaesthesiol. 1997 Mar;14(2):178-83. doi: 10.1046/j.1365-2346.1997.00106.x.
10
Prolonged myoclonus after a single bolus dose of propofol.单次推注丙泊酚后出现的持续性肌阵挛。
Anaesthesia. 2009 Nov;64(11):1254-7. doi: 10.1111/j.1365-2044.2009.06035.x.

引用本文的文献

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Description of the Content and Quality of Publicly Available Information on the Internet About Inhaled Volatile Anesthesia and Total Intravenous Anesthesia: Descriptive Study.互联网上关于吸入性挥发性麻醉和全静脉麻醉的公开可用信息的内容与质量描述:描述性研究
JMIR Perioper Med. 2023 Nov 2;6:e47714. doi: 10.2196/47714.
2
Propofol and survival: an updated meta-analysis of randomized clinical trials.丙泊酚与生存率:随机临床试验的更新荟萃分析。
Crit Care. 2023 Apr 12;27(1):139. doi: 10.1186/s13054-023-04431-8.
3
Propofol lipidic infusion promotes resistance to antifungals by reducing drug input into the fungal cell.
丙泊酚脂质输注通过减少药物进入真菌细胞来增强抗真菌药物的耐药性。
BMC Microbiol. 2008 Jan 17;8:9. doi: 10.1186/1471-2180-8-9.
4
Total intravenous anaesthesia: is it worth the cost?全静脉麻醉:是否物有所值?
CNS Drugs. 2003;17(9):609-19. doi: 10.2165/00023210-200317090-00001.
5
Cost considerations in the use of anaesthetic drugs.麻醉药物使用中的成本考量。
Pharmacoeconomics. 2001;19(5 Pt 1):469-81. doi: 10.2165/00019053-200119050-00003.