与体外受精（IVF）相比，采用合子输卵管内移植（ZIFT）进行胚胎移植可提高卵胞浆内单精子注射后的成功率。
Success rates following intracytoplasmic sperm injection are improved by using ZIFT vs IVF for embryo transfer.
作者信息
Boldt J, Schnarr P, Ajamie A, Ketner J, Bonaventura L, Colver R, Reuter L, Jarrett J
机构信息
Midwest Reproductive Medicine, Indianapolis, Indiana 46260, USA.
出版信息
J Assist Reprod Genet. 1996 Nov;13(10):782-5. doi: 10.1007/BF02066498.
PURPOSE
The purpose of this study was to analyze whether the mode of embryo transfer (ZIFT vs IVF) affected the outcome in intracytoplasmic sperm injection (ICSI) cycles.
METHODS AND RESULTS
Eighty-two ICSI cycles (42 ZIFT and 40 IVF) were analyzed. Several variables, including patient age and weight, numbers of mature eggs collected, injected, and fertilized, fertilization rate, number of fertilized eggs obtained per cycle, numbers of zygotes/embryos transferred, clinical pregnancy rate, and implantation rate, were compared. Mean patient age and weight were identical. The mean number of mature eggs collected and injected and fertilization rate were significantly higher in the ZIFT group, however, the mean numbers of zygotes/embryos transferred were identical. The clinical pregnancy and implantation rates in ZIFT cycles (52.3 and 23.2% respectively) were significantly higher than in IVF cycles (17.5 and 9.7%).
CONCLUSIONS
These data suggest that ZIFT is the more appropriate method for transfer of ICSI-derived embryos.
目的
本研究旨在分析胚胎移植方式（合子输卵管内移植术与体外受精）是否会影响卵胞浆内单精子注射周期的结局。
方法与结果
分析了82个卵胞浆内单精子注射周期（42个合子输卵管内移植术周期和40个体外受精周期）。比较了几个变量，包括患者年龄和体重、采集、注射和受精的成熟卵子数量、受精率、每个周期获得的受精卵数量、移植的受精卵/胚胎数量、临床妊娠率和着床率。患者平均年龄和体重相同。合子输卵管内移植术组采集、注射和受精的成熟卵子平均数量以及受精率显著更高，然而，移植的受精卵/胚胎平均数量相同。合子输卵管内移植术周期的临床妊娠率和着床率（分别为52.3%和23.2%）显著高于体外受精周期（17.5%和9.7%）。
结论
这些数据表明，合子输卵管内移植术是移植卵胞浆内单精子注射来源胚胎的更合适方法。
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