Ceballos-Salobreña A, Aguirre-Urizar J M, Bagan-Sebastian J V
Department of Oral Medicine, Granada University Dental School, Spain.
J Oral Pathol Med. 1996 Nov;25(10):523-6. doi: 10.1111/j.1600-0714.1996.tb01725.x.
A study was made of the oral manifestations in 396 patients with human immunodeficiency virus (HIV) infection. The following risk groups were established: intravenous drug users (79.5%), homosexuals (7.8%), homosexual intravenous drug users (3.3%), heterosexuals (8.1%) and hemophiliacs/transfusion patients (1.3%). The oral lesions, in decreasing order of frequency, were: periodontal disease (78.28%), candidiasis (65.65%), hairy leukoplakia (16.16%), herpes simplex virus lesions (5.30%). Kaposi's sarcoma (2.27%), recurrent aphthous ulceration (RAS) (1.01%), lichen planus (0.5%), non-Hodgkin's lymphoma (0.25%), tuberculous lesion of the tongue (0.25%) and ulcerations of uncertain etiology (0.25%). Attention is drawn to the greater predominance of these lesions in patients with CD4 values of less than 200/ mm3, compared with those who have higher lymphocyte counts.
对396例人类免疫缺陷病毒（HIV）感染患者的口腔表现进行了研究。确定了以下风险组：静脉吸毒者（79.5%）、同性恋者（7.8%）、同性恋静脉吸毒者（3.3%）、异性恋者（8.1%）以及血友病患者/输血患者（1.3%）。按出现频率递减顺序排列的口腔病变为：牙周病（78.28%）、念珠菌病（65.65%）、毛状白斑（16.16%）、单纯疱疹病毒病变（5.30%）、卡波西肉瘤（2.27%）、复发性阿弗他溃疡（RAS）（1.01%）、扁平苔藓（0.5%）、非霍奇金淋巴瘤（0.25%）、舌结核病变（0.25%）以及病因不明的溃疡（0.25%）。值得注意的是，与淋巴细胞计数较高的患者相比，CD4值低于200/mm³的患者中这些病变更为常见。
