流体动力应力对百日咳博德特氏菌细胞抗原的影响。
Effect of hydromechanical stress on cellular antigens of Bordetella pertussis.
作者信息
Rodriguez M E, Hozbor D F, Yantorno O M
机构信息
Centro de Investigación y Desarrollo de Fermentaciones Industriales (CINDEFI), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Argentina.
出版信息
J Ind Microbiol. 1996 Jul;17(1):53-5. doi: 10.1007/BF01570149.
Cells of Bordetella pertussis grown in a bioreactor under stirring conditions were studied to investigate the effect of shear stress on cellular-bound filamentous haemagglutinin (FHA). FHA attached to the bacterial surface, unlike extracellular FHA, was not affected at the shear levels tested. Moreover, no other cellular immunogen involved in the whole-cell protective activity seemed to be affected by hydromechanical forces.
研究了在搅拌条件下在生物反应器中生长的百日咳博德特氏菌细胞，以调查剪切应力对细胞结合丝状血凝素（FHA）的影响。与细胞外FHA不同，附着在细菌表面的FHA在测试的剪切水平下未受影响。此外，参与全细胞保护活性的其他细胞免疫原似乎也未受流体力学力的影响。
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