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多重危险因素干预试验中,特殊干预组和常规护理组在基线期及试验第1 - 6年的吸烟情况与食物、营养素摄入量及体重的关系。

Relation of smoking at baseline and during trial years 1-6 to food and nutrient intakes and weight in the special intervention and usual care groups in the Multiple Risk Factor Intervention Trial.

作者信息

Stamler J, Rains-Clearman D, Lenz-Litzow K, Tillotson J L, Grandits G A

机构信息

Department of Preventive Medicine, Northwestern University, Chicago, USA.

出版信息

Am J Clin Nutr. 1997 Jan;65(1 Suppl):374S-402S. doi: 10.1093/ajcn/65.1.374S.

DOI:10.1093/ajcn/65.1.374S
PMID:8988949
Abstract

This chapter describes dietary composition according to cigarette smoking status at baseline and changes in smoking status during follow-up for men in the special intervention (SI) and usual care (UC) groups of the Multiple Risk Factor Intervention Trial. Five patterns of smoking behavior were defined: 1) sustained nonsmoking, 2) early (years 1-2 of the trial) sustained quitting, 3) late (years 3-6 of the trial) sustained quitting, 4) recidivism, and 5) continued smoking. SI men who quit smoking showed greater favorable changes in dietary lipid composition and micronutrient intake than did continued smokers, and these changes were in many instances as great as favorable changes made by nonsmokers. On the other hand, SI men who quit smoking gained an average of 3.8 lb (1.7 kg), in contrast with nonsmokers who lost an average of 6.4 lb (2.9 kg). The gain by SI quitters was, however, less than that by UC quitters, who gained 6.5 lb (3.0 kg). Moreover, despite weight gain, net change in high-density-lipoprotein (HDL) cholesterol for SI quitters was positive. With the associated decrease in low-density-lipoprotein (LDL) cholesterol, early SI quitters had the most improvement in ratio of LDL to HDL among all subgroups. Thus, unfavorable nutritional patterns of smokers put them at double jeopardy regarding cardiovascular and other chronic diseases; additionally, long-term risks can be improved not only by smoking cessation but also by achievement of healthier eating patterns.

摘要

本章描述了多重危险因素干预试验中特殊干预(SI)组和常规护理(UC)组男性在基线时根据吸烟状况划分的饮食组成,以及随访期间吸烟状况的变化。定义了五种吸烟行为模式:1)持续不吸烟,2)早期(试验第1 - 2年)持续戒烟,3)晚期(试验第3 - 6年)持续戒烟,4)复吸,5)持续吸烟。与持续吸烟者相比,戒烟的SI组男性在饮食脂质组成和微量营养素摄入方面表现出更有利的变化,而且在许多情况下,这些变化与不吸烟者所产生的有利变化一样大。另一方面,戒烟的SI组男性平均体重增加了3.8磅(1.7千克),相比之下,不吸烟者平均体重减轻了6.4磅(2.9千克)。然而,SI组戒烟者的体重增加量小于UC组戒烟者,后者体重增加了6.5磅(3.0千克)。此外,尽管体重增加,但SI组戒烟者高密度脂蛋白(HDL)胆固醇的净变化是正向的。随着低密度脂蛋白(LDL)胆固醇相应减少,早期SI组戒烟者在所有亚组中LDL与HDL的比值改善最大。因此,吸烟者不良的营养模式使他们在患心血管疾病和其他慢性病方面面临双重风险;此外,长期风险不仅可以通过戒烟来改善,还可以通过实现更健康的饮食模式来改善。

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