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心脏手术后并发多器官功能衰竭的生活质量。

Quality of life after cardiac surgery complicated by multiple organ failure.

作者信息

Nielsen D, Sellgren J, Ricksten S E

机构信息

Department of Anesthesia and Intensive Care, Sahlgrenska University Hospital, Göteborg, Sweden.

出版信息

Crit Care Med. 1997 Jan;25(1):52-7. doi: 10.1097/00003246-199701000-00012.

Abstract

OBJECTIVE

To evaluate quality of life after prolonged multiple system intensive care treatment in cardiac surgical patients.

DESIGN

A case-control study.

SETTING

Adult 12-bed thoracic intensive care unit (ICU) at a university teaching hospital.

PATIENTS

Forty-seven patients surviving multiple organ failure requiring intensive care treatment for > or = 5 days (ICU group). Patients with a completely uncomplicated postoperative course were matched to the study group with respect to gender, age, and type and date of surgery. The Nottingham Health Profile was used to assess quality of life at least 1 yr after complicated cardiac surgery.

INTERVENTIONS

Quality of life measures were collected at least 1 yr after discharge from the ICU.

MEASUREMENTS AND MAIN RESULTS

Seventy-five percent of the patients in the ICU group suffered from multiple organ failure involving at least three organ systems, with a mean stay in the ICU of 9.0 +/- 1.2 (SEM) days. Quality of life was considerably reduced in the ICU group, with a higher total mean score of all dimensions of quality of life (22.7 +/- 2.6) compared with the control group (13.2 +/- 2.4 [SEM])(p < .01). The Nottingham Health Profile score was higher in three of six dimensions of health--i.e., energy (p < .05), physical mobility (p < .05), and emotional reactions (p < .05)--compared with the control group. A higher percentage of patients reported problems in three of six important activities of daily life--housework (p < .05), hobbies (p < .01), and sex life (p < .01)--compared with the control group.

CONCLUSION

Patients treated with prolonged multiple system intensive care after heart surgery have a poor outcome with respect to quality of life measured at least 1 yr after discharge from the ICU.

摘要

目的

评估心脏手术患者长时间多系统重症监护治疗后的生活质量。

设计

病例对照研究。

地点

一所大学教学医院的拥有12张床位的成人胸科重症监护病房(ICU)。

患者

47例多器官功能衰竭幸存者,需要重症监护治疗≥5天(ICU组)。术后过程完全无并发症的患者在性别、年龄、手术类型和日期方面与研究组进行匹配。使用诺丁汉健康量表评估复杂心脏手术后至少1年的生活质量。

干预措施

在从ICU出院后至少1年收集生活质量测量数据。

测量指标及主要结果

ICU组75%的患者出现多器官功能衰竭,累及至少三个器官系统,在ICU的平均住院时间为9.0±1.2(标准误)天。ICU组的生活质量显著降低,生活质量各维度的总平均分(22.7±2.6)高于对照组(13.2±2.4[标准误])(p<0.01)。与对照组相比,在健康的六个维度中的三个维度——即精力(p<0.05)、身体活动能力(p<0.05)和情绪反应(p<0.05)方面,诺丁汉健康量表得分更高。与对照组相比,更高比例的患者在六项重要日常生活活动中的三项——家务(p<0.05)、爱好(p<0.01)和性生活(p<0.01)方面报告存在问题。

结论

心脏手术后接受长时间多系统重症监护治疗的患者,在从ICU出院后至少1年测量的生活质量方面预后较差。

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