Lamer Christian, Harboun Marc, Knani Lyes, Moreau David, Tric Laurent, LeGuillou Jean-Luc, Gasquet Isabelle, Moreau Thierry
Département de Réanimation Polyvalente, Institut Mutualiste Montsouris, 42 Boulevard Jourdan, 75674 Paris, France.
Intensive Care Med. 2004 Aug;30(8):1594-601. doi: 10.1007/s00134-004-2260-2. Epub 2004 Apr 15.
To evaluate outcomes of patients admitted to the ICU for complications after elective surgery and to assess perceived quality of life (pQOL) in survivors.
Two-year prospective case-control study.
Twelve-bed ICU in a university-affiliated hospital.
Patients admitted to the ICU for a complication following elective surgery were included. Six months after discharge, pQOL was assessed using the Nottingham Health Profile (NHP). Results were compared to those of matched controls without complications.
None.
Of the 182 patients, 124 were alive after 6 months, among whom 116 had 6-month data and 104 of these had matched controls. Overall pQOL as assessed by the global NHP score was similar in both groups (median, 0.82 and 0.87 in cases and controls; P=0.24). NHP subscores showed significantly worse pain ( P=0.03) and physical impairment ( P=0.02) in the ICU patients. In the multivariate analysis, pQOL was better in patients with cancer as the reason for surgery ( P=0.05). Severity of illness at inclusion had no influence on subsequent pQOL, but cardiovascular dysfunction was associated with decreased energy ( P=0.04).
Although overall pQOL was satisfactory after 6 months, patients admitted to the ICU for postoperative complications had worse pain and physical impairment than controls. Whether these outcomes could be improved by early physiotherapy and aggressive pain management deserves investigation.
评估因择期手术后并发症入住重症监护病房(ICU)患者的预后,并评估幸存者的主观生活质量(pQOL)。
为期两年的前瞻性病例对照研究。
一所大学附属医院的12张床位的ICU。
纳入因择期手术后并发症入住ICU的患者。出院6个月后,使用诺丁汉健康量表(NHP)评估pQOL。将结果与无并发症的匹配对照组进行比较。
无。
182例患者中,6个月后124例存活,其中116例有6个月的数据,其中104例有匹配的对照组。两组通过全球NHP评分评估的总体pQOL相似(病例组和对照组的中位数分别为0.82和0.87;P = 0.24)。NHP子评分显示ICU患者的疼痛(P = 0.03)和身体损伤(P = 0.02)明显更差。在多变量分析中,以癌症为手术原因的患者pQOL更好(P = 0.05)。纳入时的疾病严重程度对随后的pQOL没有影响,但心血管功能障碍与能量降低有关(P = 0.04)。
尽管6个月后总体pQOL令人满意,但因术后并发症入住ICU的患者比对照组有更严重的疼痛和身体损伤。早期物理治疗和积极的疼痛管理是否能改善这些结果值得研究。