失落的和弦：微嵌合体与同种异体移植存活
The lost chord: microchimerism and allograft survival.
作者信息
Starzl T E, Demetris A J, Murase N, Trucco M, Thomson A W, Rao A S
机构信息
Pittsburgh Transplantation Institute, University of Pittsburgh Medical Center, PA 15213, USA.
出版信息
Immunol Today. 1996 Dec;17(12):577-84; discussion 588. doi: 10.1016/s0167-5699(96)10070-0.
Abstract
Recent evidence suggests that passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allografts. Here, Thomas Starzl and colleagues argure that this hematolymphopoietic chimerism provides an important framework for the interpretation of basic and therapeutically oriented transplantataion research.
摘要
最近的证据表明，过客白细胞在器官移植后迁移并产生持续的嵌合现象，这对于同种异体移植物的持续存活至关重要。在此，托马斯·斯塔兹尔及其同事认为，这种血液淋巴造血嵌合现象为解释基础和治疗导向的移植研究提供了一个重要框架。
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