含羞草决明根木中的两种新芳香成分。

Two new aromatic constitutents from the rootwood of Aeschynomene mimosifolia.

作者信息

Fullas F, Kornberg L J, Wani M C, Wall M E, Farnsworth N R, Chagwedera T E, Kinghorn A D

机构信息

Chemistry and Life Sciences Group, Research Triangle Institute, North Carolina 27709, USA.

出版信息

J Nat Prod. 1996 Feb;59(2):190-2. doi: 10.1021/np960052v.

DOI:10.1021/np960052v

PMID:8991952

Abstract

The rootwood of Aeschynomene mimosifolia Vatke (Leguminosae) has yielded a new neoflavonoid, mimosifoliol (1), and an unusual C16-styrylcycloheptenone derivative, mimosifolenone (2). The structures of these compounds were determined on the basis of spectral analysis. Compound 1 demonstrated weak activity in DNA-strand scission assay, while compound 2 was found to be inactive. Mimosifoliol (1) was inactive toward several human cell lines, while 2 was moderately active against the KB cell line.

摘要

含羞草叶合萌（豆科）的根木中分离得到一种新的新黄酮类化合物，含羞草叶酚（1），以及一种不寻常的C16-苯乙烯基环庚烯酮衍生物，含羞草叶酮（2）。通过光谱分析确定了这些化合物的结构。化合物1在DNA链断裂试验中表现出较弱的活性，而化合物2则无活性。含羞草叶酚（1）对几种人类细胞系无活性，而2对KB细胞系具有中等活性。