Jünemann A, Gusek G C, Naumann G O
Augenklinik mit Poliklinik Universität Erlangen-Nürnberg.
Klin Monbl Augenheilkd. 1996 Aug-Sep;209(2-3):117-24. doi: 10.1055/s-2008-1035290.
The penetrating keratoplasty as an early surgical procedure to present deep irreversible amblyopia in patients suffering from Peters' anomaly has shown an extremely high risk for transplantat failure.
From 1980 to 1992 20 sectoriridectomies (6 bilateral, 1 twice because of progressive corneal opacification in the area of sectoriridectomy) were performed in 13 patients with Peters' anomaly (diameter of corneal opacification greater than half of the corneal diameter). The mean age at surgery was 1 year and 9 months, the mean follow-up was 3 years and 6 months. Preoperatively the visual function was uncertain light perception in all eyes with marked horizontal nystagm. Except for two eyes (24 mm Hg) the intraocular pressure (IOP) was normal.
In 9 (47%) eyes the visual acuity was 20/500 to 20/200. One eye showed certain light fixation, one eye hand movement. In one eye the visual function remained uncertain light perception "after combined lens aspiration." One eye developed a phthisis after combined anterior vitrectomy and lens aspiration for PHPV. In three eyes, the visual outcome could not be determined certainly, in three eyes, the follow-up failed. In two eyes the IOP was regulated under topical antiglaucomatous eye drops, in the other eyes the IOP was normal.
In contrast to penetrating keratoplasty sectoriridectomy seems not to be followed by secondary glaucoma postoperatively. The visual outcome is comparable to that after early keratoplasty. We recommend "optical" sectoriridectomy as an alternative surgical approach to early penetrating keratoplasty in patients suffering from Peters' anomaly.
穿透性角膜移植术作为治疗彼得斯异常患者深度不可逆弱视的早期手术方法,显示出移植失败的极高风险。
1980年至1992年,对13例彼得斯异常患者(角膜混浊直径大于角膜直径的一半)进行了20次扇形虹膜切除术(6例双侧,1例因扇形虹膜切除区域角膜混浊进展而进行了两次)。手术时的平均年龄为1岁9个月,平均随访时间为3年6个月。术前,所有伴有明显水平眼球震颤的眼睛视觉功能均为不确定光感。除两只眼睛(眼压24mmHg)外,眼压正常。
9只眼(47%)的视力为20/500至20/200。一只眼显示有确定的光定位,一只眼能看到手动。一只眼在“联合晶状体吸出术后”视觉功能仍为不确定光感。一只眼在因永存原始玻璃体增生症进行联合前部玻璃体切除术和晶状体吸出术后发生眼球痨。三只眼的视觉结果无法确定,三只眼失访。两只眼通过局部抗青光眼眼药水控制眼压,其他眼睛眼压正常。
与穿透性角膜移植术不同,扇形虹膜切除术术后似乎不会继发青光眼。视觉结果与早期角膜移植术后相当。我们建议对患有彼得斯异常的患者,“光学”扇形虹膜切除术可作为早期穿透性角膜移植术的替代手术方法。