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[急性痢疾患者肝脏的功能活性及外周血脂多糖阳性中性粒细胞]

[Functional activity of the liver and lipopolysaccharide-positive neutrophils of peripheral blood in patients with acute dysentery].

作者信息

Malov V A, Grachev S V, Pak S G, Nekhaev S G, Likhoded V G, Semenov M A

机构信息

Department of Infection Diseases, MMA of IM Sechenov.

出版信息

Klin Med (Mosk). 1996;74(7):52-4.

PMID:8992118
Abstract

Acute phase proteins (albumin, prealbumin, transferrin, haptoglobin) and the results of spontaneous and load tests of lipopolysaccharide-positive neutrophils (LPS-PN) in peripheral blood were studied in the course of acute colitic dysentery in 34 patients. It is shown that at the height of the disease there was a fall in the levels of albumin, prealbumin, transferrin while haptoglobin levels were elevated. More persistent and pronounced changes were noted in patients with severe course of acute dysentery. In acute period of the disease there were low values of spontaneous and load LPS-PN tests depending on the disease severity. None of the above parameters returned to control levels within 5-6 days after the start of the treatment.

摘要

对34例急性结肠型痢疾患者在病程中进行了急性期蛋白(白蛋白、前白蛋白、转铁蛋白、触珠蛋白)以及外周血中脂多糖阳性中性粒细胞(LPS-PN)自发试验和负荷试验结果的研究。结果显示,在疾病高峰期,白蛋白、前白蛋白、转铁蛋白水平下降,而触珠蛋白水平升高。在急性痢疾重症患者中观察到更持久、更明显的变化。在疾病急性期,根据病情严重程度,LPS-PN自发试验和负荷试验值较低。上述参数在治疗开始后5至6天内均未恢复到对照水平。

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