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[急性肠道感染患者急性期蛋白的动态水平及外周血中性粒细胞的脂多糖结合活性]

[The dynamic levels of acute-phase proteins and of the lipopolysaccharide-bonding activity of the peripheral blood neutrophils in patients with acute intestinal infections].

作者信息

Malov V A, Grachev S V, Nekhaev S G, Likhoded V G, Brodov L E

出版信息

Ter Arkh. 1996;68(11):23-7.

PMID:9045371
Abstract

The study was made of lipopolysaccharide-binding activity of peripheral blood neutrophils (LBA) and content of albumin, prealbumin, transferrin, haptoglobin in patients with mild, moderate and severe course of acute dysentery and food poisoning. Uniformity of changes in the above parameters irrespectively of etiology of acute intestinal infections is discovered. Inhibition of LBA in acute disease, the pattern of acute-phase proteins time-course changes, i.e. reduced levels of albumin, prealbumin, transferrin and elevated ones of haptoglobin, more persistent and marked in severe course were registered.

摘要

对患有轻度、中度和重度急性痢疾及食物中毒的患者的外周血中性粒细胞脂多糖结合活性(LBA)以及白蛋白、前白蛋白、转铁蛋白、触珠蛋白含量进行了研究。发现上述参数的变化具有一致性,与急性肠道感染的病因无关。在急性疾病中LBA受到抑制,观察到急性期蛋白的时程变化模式,即白蛋白、前白蛋白、转铁蛋白水平降低,触珠蛋白水平升高,且在重症病程中更为持久和明显。

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