• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Glucagon and its receptor in various tissues.

作者信息

Christophe J

机构信息

Department of Experimental Surgery Medical School, Université Libre de Bruxelles, Belgium.

出版信息

Ann N Y Acad Sci. 1996 Dec 26;805:31-42; discussion 42-3. doi: 10.1111/j.1749-6632.1996.tb17471.x.

DOI:10.1111/j.1749-6632.1996.tb17471.x
PMID:8993391
Abstract
摘要

相似文献

1
Glucagon and its receptor in various tissues.
Ann N Y Acad Sci. 1996 Dec 26;805:31-42; discussion 42-3. doi: 10.1111/j.1749-6632.1996.tb17471.x.
2
Glucagon receptors: from genetic structure and expression to effector coupling and biological responses.
Biochim Biophys Acta. 1995 May 8;1241(1):45-57. doi: 10.1016/0304-4157(94)00015-6.
3
Cloning and expression of a human glucagon receptor.
Biochem Biophys Res Commun. 1994 Jan 14;198(1):328-34. doi: 10.1006/bbrc.1994.1046.
4
Expression, purification and preliminary characterization of glucagon receptor extracellular domain.胰高血糖素受体胞外域的表达、纯化及初步表征
Protein Expr Purif. 2013 Jun;89(2):232-40. doi: 10.1016/j.pep.2013.04.004. Epub 2013 Apr 15.
5
Glucagon and GLP-1 receptors: lessons from chimeric ligands and receptors.胰高血糖素与胰高血糖素样肽-1受体:嵌合配体和受体带来的启示。
Acta Physiol Scand. 1996 Jul;157(3):343-5. doi: 10.1046/j.1365-201X.1996.37259000.x.
6
Structural and functional characterizations of the 5'-flanking region of the mouse glucagon receptor gene: comparison with the rat gene.小鼠胰高血糖素受体基因5'-侧翼区的结构与功能特性:与大鼠基因的比较。
Biochem Biophys Res Commun. 2000 Jun 16;272(3):912-21. doi: 10.1006/bbrc.2000.2876.
7
Identification of key residues for the binding of glucagon to the N-terminal domain of its receptor: an alanine scan and modeling study.鉴定胰高血糖素与其受体 N 端结构域结合的关键残基:一种丙氨酸扫描和建模研究。
Horm Metab Res. 2012 Oct;44(11):804-9. doi: 10.1055/s-0032-1321877. Epub 2012 Aug 14.
8
Expression of proglucagon and proglucagon-derived peptide hormone receptor genes in the chicken.鸡中胰高血糖素原及胰高血糖素原衍生肽激素受体基因的表达
Gen Comp Endocrinol. 2008 Apr 1;156(2):323-38. doi: 10.1016/j.ygcen.2008.01.014. Epub 2008 Jan 26.
9
Topographical amino acid substitution in position 10 of glucagon leads to antagonists/partial agonists with greater binding differences.胰高血糖素第10位的氨基酸发生拓扑学取代会产生具有更大结合差异的拮抗剂/部分激动剂。
J Med Chem. 1996 Jun 21;39(13):2449-55. doi: 10.1021/jm960130b.
10
Positively charged residues at positions 12, 17, and 18 of glucagon ensure maximum biological potency.
J Biol Chem. 1998 Apr 24;273(17):10308-12. doi: 10.1074/jbc.273.17.10308.

引用本文的文献

1
Glucagon, cyclic AMP, and hepatic glucose mobilization: A half-century of uncertainty.胰高血糖素、环腺苷酸和肝糖动员:半个世纪的不确定性。
Physiol Rep. 2022 May;10(9):e15263. doi: 10.14814/phy2.15263.
2
Effect of Dietary Macronutrients on Postprandial Glucagon and Insulin Release in Obese and Normal-Weight Women.膳食常量营养素对肥胖和正常体重女性餐后胰高血糖素和胰岛素释放的影响。
Int J Endocrinol. 2020 Apr 30;2020:4603682. doi: 10.1155/2020/4603682. eCollection 2020.
3
Gut hormone polyagonists for the treatment of type 2 diabetes.用于治疗 2 型糖尿病的肠促胰岛素多效激动剂。
Peptides. 2018 Feb;100:190-201. doi: 10.1016/j.peptides.2017.12.021.
4
Glucagon regulates its own synthesis by autocrine signaling.胰高血糖素通过自分泌信号调节自身的合成。
Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20925-30. doi: 10.1073/pnas.1212870110. Epub 2012 Dec 3.
5
Minireview: Glucagon in stress and energy homeostasis.综述:胰高血糖素在应激和能量平衡中的作用。
Endocrinology. 2012 Mar;153(3):1049-54. doi: 10.1210/en.2011-1979. Epub 2012 Jan 31.
6
CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability.CREB 和 ChREBP 对能量可用性的反应相反,调节 SIRT1 的表达。
EMBO Rep. 2011 Sep 30;12(10):1069-76. doi: 10.1038/embor.2011.151.
7
Differential expression of glucagon and glucagon-like peptide 1 receptors in mouse pancreatic alpha and beta cells in two models of alpha cell hyperplasia.两种胰岛α细胞增生模型中鼠胰岛α和β细胞中胰高血糖素和胰高血糖素样肽 1 受体的差异表达。
Mol Cell Endocrinol. 2009 Nov 13;311(1-2):69-76. doi: 10.1016/j.mce.2009.07.024. Epub 2009 Jul 30.
8
Low doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans.低剂量的双酚A和己烯雌酚通过朗格汉斯胰岛内完整细胞中的一种非经典膜雌激素受体损害胰腺α细胞中的Ca2+信号。
Environ Health Perspect. 2005 Aug;113(8):969-77. doi: 10.1289/ehp.8002.