综述：胰高血糖素在应激和能量平衡中的作用。
Minireview: Glucagon in stress and energy homeostasis.
机构信息
Department of Investigative Medicine, Commonwealth Building, Imperial College London, Hammersmith Campus, Du Cane Road, London W12 0HS, United Kingdom.
出版信息
Endocrinology. 2012 Mar;153(3):1049-54. doi: 10.1210/en.2011-1979. Epub 2012 Jan 31.
Abstract
Glucagon is traditionally thought of as an antihypoglycemic hormone, for example in response to starvation. However, it actually increases energy expenditure and has other actions not in line with protection from hypoglycemia. Furthermore, it is often found to be elevated when glucose is also raised, for example in circumstances of psychological and metabolic stress. These findings seem more in keeping with glucagon having some role as a hormone enhancing the response to stress.
摘要
胰高血糖素传统上被认为是一种抗低血糖激素，例如在饥饿时。然而，它实际上会增加能量消耗，并具有其他与防止低血糖不一致的作用。此外，当葡萄糖也升高时，例如在心理和代谢应激的情况下，通常会发现胰高血糖素升高。这些发现似乎更符合胰高血糖素作为一种激素增强应激反应的作用。
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