Macharia W M
Department of Paediatrics, Unversity of Nairobi, Kenya.
East Afr Med J. 1996 Oct;73(10):647-50.
Following the outbreak of human immune deficiency virus (HIV) infection in the early 1980's, there has been an increase in reported cases of Kaposi's sarcoma, among other childhood malignancies, from the East and Central African region. To assess the status of childhood cancers at Kenyatta National Hospital during the AIDS epidemic period and to compare the findings with those obtained before the outbreak, relevant data were extracted from ward admission registers for all children admitted in the paediatric wards and in whom a diagnosis of a malignant disease was confirmed. The data were summarised in tables and bar charts. The hospital based prevalence for malignant diseases was 1.27% (CI = 1.23,1.31). Lymphoma (51.3%), leukaemia (21.3%), nephroblastoma (8.5%) and rhabdomyosarcoma (5.2%) are the most common childhood cancers. Compared with earlier studies, the frequency of acute lymphoblastic leukaemia, Hodgkin's disease and rhabdomyosarcoma appear to have increased. Despite the AIDS epidemic, there has been no obvious increase in number of cases of Kaposi's sarcoma.
20世纪80年代初人类免疫缺陷病毒（HIV）感染爆发后，东非和中非地区报告的卡波西肉瘤病例以及其他儿童恶性肿瘤病例有所增加。为评估艾滋病流行期间肯雅塔国家医院儿童癌症的状况，并将结果与疫情爆发前的结果进行比较，从儿科病房收治的所有确诊患有恶性疾病的儿童的病房入院登记册中提取了相关数据。数据汇总在表格和条形图中。该医院恶性疾病的患病率为1.27%（置信区间=1.23,1.31）。淋巴瘤（51.3%）、白血病（21.3%）、肾母细胞瘤（8.5%）和横纹肌肉瘤（5.2%）是最常见的儿童癌症。与早期研究相比，急性淋巴细胞白血病、霍奇金病和横纹肌肉瘤的发病率似乎有所增加。尽管有艾滋病疫情，但卡波西肉瘤的病例数并未明显增加。
