Winreich J, Pedersen O, Dinesen K
Acta Med Scand. 1977;202(1-2):125-30.
After the intake of approximately 24 g wheat bran daily for 5 weeks, 25 trainee nurses showed no changes in the serum levels of cholesterol, triglyceride, calcium or total 3 alpha-hydroxycholanic acid. On the other hand, the study revealed a reduced intestinal transit time with good correlation to an increased frequency of bowel movements. Average body weight fell significantly, by 0.4 kg. The daily caloric intake remained constant throughout the study period, whereas the calcium intake was significantly increased. Among the serum parameters and the dietary constituents, good correlation was found only between serum cholesterol and the dietary cholesterol content. In addition, an inverse relationship was demonstrated between the serum levels of cholesterol and total 3 alpha-hydroxycholanic acid. The significance of this observation is as yet unknown.
25名实习护士连续5周每天摄入约24克麦麸后，其血清中的胆固醇、甘油三酯、钙或总3α-羟基胆酸水平均未发生变化。另一方面，研究显示肠道转运时间缩短，且与排便频率增加密切相关。平均体重显著下降，降幅为0.4千克。在整个研究期间，每日热量摄入保持恒定，而钙摄入量显著增加。在血清参数和饮食成分中，仅发现血清胆固醇与饮食胆固醇含量之间存在良好相关性。此外，血清胆固醇水平与总3α-羟基胆酸之间呈负相关。这一观察结果的意义尚不清楚。
