Lahucký J, Liptaj T
Výskumný ústav zivocísnej výroby, Nitra.
Cesk Fysiol. 1996 Dec;45(4):203-10.
Introduction of nuclear magnetic resonance has enabled direct measurements of muscle metabolism in vitro and in vivo. In the presented paper some theoretical and practical applications mainly 31P NMR spectroscopy in research and diagnostics of muscle skeletal diseases are given. In spite of some limitations, the most important advantage of NMR technique is its non-destructive character, the possibility of simultaneous observation of several phosphorylated metabolites in a muscle tissue and the simple method of sample preparation. 31P NMR is a useful tool for studying and detection of muscle diseases and at the same time for its safety for patients.
核磁共振技术的引入使得在体外和体内直接测量肌肉代谢成为可能。在本文中,介绍了一些主要利用³¹P核磁共振波谱技术在肌肉骨骼疾病研究和诊断中的理论及实际应用。尽管存在一些局限性,但核磁共振技术最重要的优点是其无损特性、能够同时观察肌肉组织中多种磷酸化代谢物以及简单的样品制备方法。³¹P核磁共振是研究和检测肌肉疾病的有用工具,同时对患者也很安全。