Mandel E M, Lewinski U, Gafter U, Weiss S, Freidin N, Djaldetti M
Am J Med Sci. 1977 Jul-Aug;274(1):61-7. doi: 10.1097/00000441-197707000-00008.
Electron microscope examination of the liver biopsies of 33 patients revealed the presence of intramitochondrial crystalline inclusions (IMCI) in ten of them. Three patients suffered from iron deficiency anemia, porphyria, and malignant melanoma, conditions not reported to be associated with IMCI. Comparison of the clinical and laboratory findings of patients with and without IMCI did not show significant difference, or a clue for clarifying the nature of this phenomenon. Although these inclusions were reported in normal individuals, the possibility that they are the result of liver damage is not excluded.
对33例患者的肝脏活检组织进行电子显微镜检查发现，其中10例存在线粒体内结晶包涵体（IMCI）。3例患者分别患有缺铁性贫血、卟啉病和恶性黑色素瘤，这些病症尚无与IMCI相关的报道。对有和没有IMCI的患者的临床和实验室检查结果进行比较，未发现显著差异，也没有找到可阐明这一现象本质的线索。尽管在正常个体中也有这些包涵体的报道，但不排除它们是肝脏损伤结果的可能性。
