Mandel E M, Fishman P, Kissin E, Har-Zaav L, Djaldetti M
Acta Hepatogastroenterol (Stuttg). 1976 Jun;23(3):182-6.
The case of a female patient with hyperthyroidism and slightly impaired liver function is described. Histological examination of liver biopsy did not reveal any pathological findings. Electron microscopic examination revealed crystalline inclusions in a great number of the mitochondria of the liver cells, as well as increased size of the mitochondira. Similar findings were obtained upon examination of a liver biopsy performed six months after start of treatment for hyperthyroidism. Examination of the skin, muscle and white blood cells did not show the presence of such inclusions in the mitochondria. The significance of these findings in the liver cells is discussed.
本文描述了一名患有甲状腺功能亢进且肝功能稍有受损的女性患者的病例。肝活检的组织学检查未发现任何病理结果。电子显微镜检查发现肝细胞的大量线粒体中有晶体包涵体，并且线粒体尺寸增大。在开始治疗甲状腺功能亢进六个月后进行的肝活检检查也得到了类似的结果。对皮肤、肌肉和白细胞的检查未显示线粒体中存在此类包涵体。文中讨论了这些肝细胞中发现的意义。
